Buy MT1 Peptide
MT1 peptide (Afamelanotide / Melanotan 1) is a synthetic 13-amino-acid peptide engineered as an analog of endogenous $\alpha$-melanocyte-stimulating hormone ($\alpha$-MSH). Incorporating a specific $\text{D-Phe}^7$ amino acid substitution into its linear backbone, MT1 peptide offers increased structural stability against enzymatic cleavage by serum proteases compared to native peptides. In laboratory settings, MT-1 peptide serves as a baseline reference standard for studying melanocortin receptor (MC1R) binding kinetics, intracellular cAMP pathway activation, and melanogenesis signaling pathways in melanocyte culture models.
Solubilization & Reconstitution of MT1 Peptide
To prepare MT-1 peptide for automated pipetting or cellular assays, reconstitute the lyophilized powder using sterile bacteriostatic water, sterile water, or phosphate-buffered saline (PBS).Working Concentration: A standard $1.0\text{ mg/mL}$ to $2.0\text{ mg/mL}$ concentration provides complete dissolution and standard solution density.Agitation Protocol: Gently swirl the vial until the solute is completely suspended. Avoid mechanical vortexing, rapid shaking, or sonicating MT-1 peptide solutions, as mechanical shear stress can disrupt peptide tertiary structures.
Handling & Stability Guidelines for MT1 Peptide
Lyophilized Storage: Store dry MT1 peptide vials desiccated at $-20^\circ\text{C}$ to $-80^\circ\text{C}$ for long-term stability. Keep containers sealed to prevent moisture absorption.Liquid Phase Handling: Once hydrated, MT-1 peptide solutions should be split into working aliquots to prevent damage from repeated freeze-thaw cycles. Store liquid aliquots at $2^\circ\text{C}$ to $8^\circ\text{C}$ for short-term evaluation, or $-80^\circ\text{C}$ for extended storage. Shield all solutions from direct ultraviolet light.
MT1 peptide supplied by AU Peptides Store
Every lot of MT-1 peptide supplied by AU Peptides Store undergoes rigorous analytical quality control before distribution:High-Performance Liquid Chromatography (HPLC): Confirms $\ge 99.0\%$ chromatographic purity with low organic impurities.Liquid Chromatography–Mass Spectrometry (LC-MS): Verifies correct molecular mass ($1646.85\text{ g/mol}$) and exact sequence order.Regulatory Statement: MT1 peptide is supplied strictly as a high-purity laboratory reference chemical intended exclusively for in vitro scientific research, biochemical testing, and laboratory assays.
